Learning Intention: To understand nucleic acids as information molecules that encode instructions for the synthesis of proteins in cells and the processes of transcription and translation in cells. Students will also understand protein functional diversity and the nature of the proteome as well as the functional importance of the four hierarchal levels of protein structure. They will perform experiments that demonstrate the effect of temperature and pH on enzymes.
- Catalase is an enzyme found in liver extract that breaks down hydrogen peroxide (H2O2) into water and oxygen.
- Hydrogen peroxide is a toxic product of digestion that needs to be eliminated from the body. Water and oxygen are the safe products of hydrogen peroxide breakdown.
- Primary structure of protein – order of amino acids
- Secondary structure – alpha helix, beta pleated sheets or random coils
- Tertiary structure – folding of the polypeptide chain due to disulphide bridges and other attractions or repulsions between molecules.
- Quarternary structure – two or more polypeptide chains folded together to form a complex protein.
- Basics of DNA (YouTube, 1.47min)
- Structure of DNA (YouTube, 5.58min) (3′ to 5′ structure,purines and pyramidines)
- Transcription and Translation (YouTube, 6.26min)
- 3D Animation of transcription and translation (DNA Learning Centre, 1.52min)
- Transcription and translation overview (YouTube, 13.17min) Neat drawings!
- Khan Acadamy (YouTube, 15.23min)