Category Archives: Videos

Signalling molecules, antigens and the immune system

How do cells communicate? In this area of study students focus on how cells receive specific signals that elicit a particular response. Students apply the stimulus-response model to the cell in terms of the types of signals, the position of receptors, and the transduction of the information across the cell to an effector that then initiates a response. Students examine unique molecules called antigens and how they elicit an immune response, the nature of immunity and the role of vaccinations in providing immunity. They explain how malfunctions in signalling pathways cause various disorders in the human population and how new technologies assist in managing such disorders.

Outcome 2 On completion of this unit the student should be able to apply a stimulus-response model to explain how cells communicate with each other, outline immune responses to invading pathogens, distinguish between the different ways that immunity may be acquired, and explain how malfunctions of the immune system cause disease.

In Area of Study 2: How do cells communicate? we study cellular signals (signalling molecules, signal transduction and apoptosis); responding to antigens (including antigens, innate and adaptive immunity and the lymphatic system) and the immune system (including diseases of the immune system and cancer immunotherapy). The following links are some resources for study in these topics.

Chapter 6: Cellular Signals

Chapter 7: Responding to antigens

Chapter 8: Immunity, immune malfunctions and immunotherapy

Signal Transduction and Apoptosis

Last lesson we learned about the different types of signalling molecules (plant and animal hormones, neurotransmitters, cytokines and phermones). Today we will learn what happens when these signalling molecules reach their target cells, causing a response in the cell. Lipophobic (hydrophilic) signalling molecules cannot pass through the cell membrane, so they rely on complementary protein receptors that are embedded in the cell membrane. Once the signalling molecule – or ligand – binds to the receptor protein, secondary messenger molecules are released inside the target cell. Learn more about the specifics of signal transduction here:

Signal transduction from the Penguin Prof Channel

Signal transduction from Mr Bozeman (simple animated diagrams with commentary)

In the video above, observe one of the consequences of signal transduction – apoptosis or programmed cell death.

Week 6: Energy transformations in cells – photosynthesis

Learning intention: Students will understand the energy transformations from sunlight to chemical energy in the process of photosynthesis.

Watch the following videos and take Cornell notes. Especially pay attention to the products and reactants of the light-dependent and light-independent (Calvin cycle) parts of the reaction.

Human intervention in evolution

GMO_Papaya_sunset

Image source

This fruit is from a genetically modified papaya plant, bred to reduce the risk of disease. How are genetically modified organisms created? (YouTube video, 5.31min)

Quizlet – Flashcards for Chapter 16

While genetic techniques have certainly provided health benefits to our society (disease diagnosis and therapies, production of insulin and increased production of more nutritious and disease resistant foods), there are also community concerns about the ways that these technologies are being used and the future consequences. ABC Splash have some short videos that outline some of the issues of genetic technologies:

The Science of Human Evolution

human_evolution

Video Source (YouTube, 54.42 min)

  1. What vestigial organ, a remnant from our primate ancestors, is apparent in humans?
  2. Which species does the video refer to as our “distant cousins”?
  3. Name three characteristics that we share with these monkeys.
  4. Notharctus tenebrosus is a fossil that scientists believe to be a common ancestor of humans – how old is this fossil?
  5. What feature of this fossil’s hand is important for climbing and gripping objects?
  6. How was colour vision an important evolutionary advantage in early primates?
  7. What genetic mutation occurred to allow primates to see in colour like humans?
  8. What sense diminished as humans evolved high-colour vision? What evidence is there for this?
  9. ‘Lucy’ is a 3.2 million year old fossil from Ethiopia – why is this fossil significant?
  10. What advantages does this particular characteristic give the species?
  11. What disadvantages does bipedalism have for modern humans?
  12. What characteristic of stone-age man is an indication that human ancestors had the ability for complex thought, together with highly developed hand-eye co-ordination?
  13. In what test do 3 month old monkeys out-perform human babies?
  14. What fundamental brain architecture do all vertebrates, including sharks and humans, share?

Unit 4: Area of Study 2: Change over time

Sperm_whale_drawing_with_skeleton

Image source

“The theory of evolution by natural selection, first formulated in Charles Darwin’s book “On the Origin of Species” in 1859, is the process by which organisms change over time as a result of changes in heritable physical or behavioral traits.”

“Natural selection is the process whereby organisms better adapted to their environment tend to survive and produce more offspring. The theory of its action was first fully expounded by Charles Darwin, and it is now regarded as be the main process that brings about evolution.”

What is the evidence for evolution? from Stated Clearly (YouTube, 11.21min)

  • Fossil evidence – organisms have changed over time and some have become extinct
  • Comparative morphology (anatomy) – there are similarities between some organisms that suggest a common ancestor
  • DNA evidence – Similar species have more genes in common than dissimilar species, suggesting a common ancestor; Chimpanzees and humans have 99% of their DNA in common
  • Distribution of species (biogeography) shows that islands have unique species, due to an original inhabitant becoming adapted to its’ environment over many generations, by natural selection
  • Similarities of embryos suggest that all vertebrates have a common ancestry

Tree of Life video HD with David Attenborough (YouTube, 6.29 min) – Complete the student worksheet – Highlighting important stages in evolution. 

Week 3: Biochemical Processes

living_cells

Image source

The biological cell is not the static, neat drawing you find in text books, but a dynamic, differentiated, three-dimensional, living unit with many specialised processes occurring simultaneously. You should already know the basic structure and function of the cell, including the main organelles. This animated video shows some of the inner life of a cell – can you identify the cell membrane, embedded proteins and ribosomes? Over the next fortnight you will need to better understand the following biochemical cellular processes:

Exam Revision

Welcome back and thanks for your patience while I have been on study leave. There are only two weeks left before the Unit 3/4 Biology exam on Friday 30th October, so you should have already done the following:

  1. Written out a clear and concise set of study notes, outlining the main concepts in each Area of Study.
  2. Completed practice exams (available at the VCAA website) and identified areas where you need to do further revision.
  3. Joined the Elevate Education #elevatebio Video Series at http://bio.elevateeducation.com/
  4. You may also like to join the Study.com site for a five-day free trial and access their Immunology resources.

Some students have mentioned that they are having most difficulty remembering the cells involved and sequence of events of the cell cycle and immunology. These quick videos and other resources may assist with your revision:

Food webs and energy transfer

Food_web

Image source

Food chains illustrate the relationship between producers and consumers, showing the different trophic levels in an ecosystem. Because living organisms usually have more than one source of food, these food chains are often linked together, forming food webs. Food webs assist us to identify herbivores, carnivores, omnivores, scavengers, detritivores and decomposers in a community.

Not all relationships within an ecological community are predatory or feeding relationships. Some important relationships are parasitic, mutualistic (both organisms benefit), commensalism (one benefits, the other is not harmed) or parasitism (one benefits and the other is harmed, but usually not killed).

Cupcake mitosis

mitosis_cakes#3

Students in Year 11 Biology are learning the phases of mitosis, so we baked and decorated these cupcakes. Students now have a good understanding of what happens inside the nucleus during:

  • Interphase
  • Prophase
  • Metaphase
  • Anaphase
  • Telophase and
  • Cytokinesis.

Watch the Cells Alive Interactive and describe where in each cycle are the three checkpoints that allow DNA replication and mitosis to continue. Why is it incorrect to suggest that the cell is “resting” during interphase, between mitotic cycles?