Apoptosis – programmed cell death

“Apoptosis is a process where a cell is degraded in order for it to be ultimately engulfed and recycled. Apoptosis can occur when a cell has become mutated and is on the verge of becoming a cancer. Apoptosis is also the reason why we don’t have webbed hands and feet. What basically happens is that the killer “t” cell communicates with the diseased cell by adhering to it by binding its death ligand to the death receptor on the diseased cell. This causes adapter proteins to attach to the cytosolic side of the receptor. This leads to a signal cascade which involves the recruitment of various other proteins and ultimately results in the death of the cell.” ~ bowlerdude on YouTube.

  1. What is the difference between apoptosis and necrosis?
  2. What is the difference between apoptosis and autophagy?

 

 

8 thoughts on “Apoptosis – programmed cell death

  1. Chloe

    What is the difference between apoptosis and necrosis?
    While apoptosis is the process of programed cell death which may occur in multicellular organisms, necrosis is a form of cell injury which will result in the premature death of a cell in living tissue by autolysis. Apoptosis is also considered as advantageous for the organism’s lifecycle, whereas necrosis is simply considered as a form of traumatic death resulting from acute cellular injury.

    What is the difference between apoptosis and autophagy?
    Unlike apoptosis, autophagy is a catabolic mechanism which sees the degradation of unnecessary and dysfunctional components of the cell through the actions of lysosomes. This breakdown of cellular components is advantageous for the cell as it ensures survival during starvation by maintaining the cellular energy levels.

  2. Kirsten

    1. What is the difference between apoptosis and necrosis?
    Apoptosis is the death of cells which occurs as a normal and controlled part of an organism’s growth or development whereas necrosis is the death of most or all of the cells in an organ or tissue due to disease, injury, or failure of the blood supply.
    2. What is the difference between apoptosis and autophagy?
    Autophagy is a catabolic mechanism that involves cell degradation of dysfunctional or unnecessary cellular components through the actions of lysosomes whereas apoptosis in the death of a cells that happens as a controlled and normal part of the growth and development of an organism.

  3. Josh

    Apoptosis is like cell suicide. The cell initiates its death itself. Necrosis occurs due to severe injury caused by external forces. Autophagy is when a cell degrades and digests dysfunctional or unnecessary bodies within its structure.

  4. samuel96

    What is the difference between apoptosis and necrosis?
    – Apoptosis is programmed cell death, where as necrosis is premature cell death that occurs daue to accidental damage to the cell.
    What is the difference between apoptosis and autophagy?
    – Autophagy is the process of breaking down unnecessary or dysfunctional cell organelles to provide energy for the cell during times of stress whereas apoptosis is the complete breakdown of an entire infected cell.

  5. Belinda

    1. Apoptosis occurs naturally and is programmed or targeted. Necrosis is caused by external factors like toxins, damage, infection or trauma. Necrosis is the premature death of a cell by autolysis. Necrosis is nearly always detrimental and can be fatal, compared to apoptosis which is nearly always beneficial.
    2. Apoptosis is ‘self- killing’ where as Autophagy is ‘self- eating’. Autophagy involves cells ‘eating’ unnecessary or dysfunctional cellular components.

  6. Rachael

    Apoptosis is the death of cells which occurs as part of a standard and controlled portion of the growth or development of an organism. Where necrosis is different to apoptosis because it is the death of the majority of cells in a tissue or organ caused by either, injury, disease or failure of the blood supply.

    Autophagy differs from apoptosis because autophagy involves cell breakdown of either dysfunctional or needless cellular components, occurring through actions of lysosomes where apoptosis is part of a controlled portion of development or growth of an organism.

  7. Jess Lewis

    1. What is the difference between apoptosis and necrosis?
    Apoptosis is the process of programmed cell death that may occur in multicellular organisms. Biochemical events lead to the cells characteristics changing and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, and chromosomal DNA fragmentation. Necrosis occurs when a cell is damaged by an external force including poison, bodily injury, infection or getting cut off from the blood supply (heart attack or stroke). The cell death causes inflammation which can cause further injury within the body.
    2. What is the difference between apoptosis and autophagy?
    Autophagy, is the basic catabolic mechanism that involves cell degradation of unnecessary or dysfunctional cellular components through the actions of lysosomes. This breakdown ensures cellular survival during starvation by maintaining cellular energy levels. Whereas apoptosis is cell death.

  8. Indi

    1. What is the difference between apoptosis and necrosis?
    Apoptosis is the natural death of cells and sometimes called programmed cell death, that may occur in multicellular organisms. Biochemical events lead to characteristic cell changes that include cell shrinkage, nuclear fragmentation and chromosomal DNA fragmentation. Whereas necrosis occurs when a cell is damaged by an external force such as a poison, bodily injury, an infection or getting cut off from the blood supply. When cells die from necrosis, it’s a rather messy affair. The death causes inflammation that can cause further distress or injury within the body. Apoptosis also differs from necrosis in that it’s essential to human development. For example, in the womb, our fingers and toes are connected to one another by a sort of webbing. Apoptosis is what causes that webbing to disappear, leaving us with 10 separate digits.

    2. What is the difference between apoptosis and autophagy?
    Autophagy is the basic catabolic mechanism that involves cell degradation of unnecessary or dysfunctional cellular components through the actions of lysosomes. The breakdown of cellular components can ensure cellular survival during starvation by maintaining cellular energy levels. Autophagy, if regulated, ensures the synthesis, degradation and recycling of cellular components. During this process, targeted cytoplasmic constituents are isolated from the rest of the cell within the autophagosome, which are then fused with lysosomes and degraded or recycled.

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